2022-12-20 18:32:09 UTC

13 files changed, 45 insertions, 60 deletions

diff --git a/metadata/md5-cache/net-ftp/ncftp-3.2.6-r4 b/metadata/md5-cache/net-ftp/ncftp-3.2.6-r4
deleted file mode 100644
index 0d67ade827e0..000000000000
--- a/metadata/md5-cache/net-ftp/ncftp-3.2.6-r4
+++ /dev/null
@@ -1,15 +0,0 @@
-BDEPEND=virtual/pkgconfig sys-devel/gnuconfig >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.5:1.16 ) >=sys-devel/autoconf-2.71-r5 >=sys-devel/libtool-2.4.7
-DEFINED_PHASES=configure install prepare
-DEPEND=sys-libs/ncurses:=
-DESCRIPTION=An extremely configurable ftp client
-EAPI=8
-HOMEPAGE=https://www.ncftp.com/
-INHERIT=autotools toolchain-funcs
-IUSE=pch
-KEYWORDS=~alpha amd64 arm ~hppa ~ia64 ~mips ppc ppc64 ~riscv ~s390 sparc x86 ~amd64-linux ~x86-linux ~ppc-macos ~x64-macos ~sparc-solaris ~x86-solaris
-LICENSE=Clarified-Artistic
-RDEPEND=sys-libs/ncurses:=
-SLOT=0
-SRC_URI=https://ftp.mirrorservice.org/sites/ftp.ncftp.com/ncftp/ncftp-3.2.6-src.tar.xz
-_eclasses_=gnuconfig	b6b3e92f8b8c996400074b5f61a59256	toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	multilib	5ca4e49abed8e3a2f7b56920eadee157	libtool	241a8f577b9781a42a7421e53448a44e	autotools	6dcd6b6a486e79928e1243ff9ba41fcc
-_md5_=6394b339feb7b591d1350d8a180fd295
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2020.4-r1 b/metadata/md5-cache/sci-chemistry/gromacs-2020.4-r1
index af54aaa9cfaa..eade5d8c5832 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2020.4-r1
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2020.4-r1
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=7
@@ -7,10 +7,10 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=X blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 KEYWORDS=amd64 arm x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
-REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2020.4
 SRC_URI=http://ftp.gromacs.org/gromacs/gromacs-2020.4.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2020.4.pdf ) test? ( http://ftp.gromacs.org/regressiontests/regressiontests-2020.4.tar.gz )
 _eclasses_=toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	multilib	5ca4e49abed8e3a2f7b56920eadee157	bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	edos2unix	33e347e171066657f91f8b0c72ec8773	strip-linguas	ac3ee41ee2d31d8c41a77c0838320cc7	wrapper	4a1902f969e5718126434fc35f3a0d9c	eutils	8f942ebdcf04334697649d4a0bf65a32	flag-o-matic	69394e25812406faa1f90edaf4969395	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	xdg-utils	ac0e315a3688929e34ac75b139e7349a	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	multibuild	d26d81f242cb193d899a72bca423d0bd	eapi8-dosym	cd7d420bb5be5ee079f27239ce76b8f5	python-utils-r1	6a75203e8a499f0fb42971452ce15388	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55
-_md5_=a9d58ceefb0bc663f763b817d2cd1717
+_md5_=07bad0642c3d9dc07f1e3e13abc97082
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2020.7 b/metadata/md5-cache/sci-chemistry/gromacs-2020.7
index cbc9ec4cb630..1c5352b19649 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2020.7
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2020.7
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,10 +7,10 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=X blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 KEYWORDS=~amd64 ~arm ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
-REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2020.7
 SRC_URI=http://ftp.gromacs.org/gromacs/gromacs-2020.7.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2020.7.pdf ) test? ( http://ftp.gromacs.org/regressiontests/regressiontests-2020.7.tar.gz )
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-_md5_=a9dec67c45cdabcd7dd00665d56788ef
+_md5_=45e1a1e67a45fd5f3ef7fa0499fae879
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2021.3-r1 b/metadata/md5-cache/sci-chemistry/gromacs-2021.3-r1
index 9f6eb343ccab..b0e9f79d7eae 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2021.3-r1
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2021.3-r1
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,10 +7,10 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=X blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 KEYWORDS=amd64 arm x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
-REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2021.3
 SRC_URI=http://ftp.gromacs.org/gromacs/gromacs-2021.3.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2021.3.pdf ) test? ( http://ftp.gromacs.org/regressiontests/regressiontests-2021.3.tar.gz )
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diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2021.5 b/metadata/md5-cache/sci-chemistry/gromacs-2021.5
index 113619159299..cc95db49fe0e 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2021.5
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2021.5
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,10 +7,10 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=X blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 KEYWORDS=~amd64 ~arm ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
-REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2021.5
 SRC_URI=http://ftp.gromacs.org/gromacs/gromacs-2021.5.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2021.5.pdf ) test? ( http://ftp.gromacs.org/regressiontests/regressiontests-2021.5.tar.gz )
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diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2021.6 b/metadata/md5-cache/sci-chemistry/gromacs-2021.6
index 167afcc3b52b..2a1a48bc695c 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2021.6
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2021.6
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,10 +7,10 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=X blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 KEYWORDS=~amd64 ~arm ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
-REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2021.6
 SRC_URI=http://ftp.gromacs.org/gromacs/gromacs-2021.6.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2021.6.pdf ) test? ( http://ftp.gromacs.org/regressiontests/regressiontests-2021.6.tar.gz )
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diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2021.9999 b/metadata/md5-cache/sci-chemistry/gromacs-2021.9999
index 12ae20dfd1e7..913f8cc89b32 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2021.9999
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2021.9999
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,9 +7,9 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=X blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
 PROPERTIES=live
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
-REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit:= ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2021.9999
 _eclasses_=toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	multilib	5ca4e49abed8e3a2f7b56920eadee157	bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	flag-o-matic	69394e25812406faa1f90edaf4969395	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	xdg-utils	ac0e315a3688929e34ac75b139e7349a	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	multibuild	d26d81f242cb193d899a72bca423d0bd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	git-r3	2347f8fe2d392b2a091191f94be37e6f
-_md5_=37783db6fed45127d7398fa432dec03d
+_md5_=bb8bd88cce4075e30ad5276a98238556
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2022.3 b/metadata/md5-cache/sci-chemistry/gromacs-2022.3
index 8f8069b8f629..d0b99647fc13 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2022.3
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2022.3
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,10 +7,10 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=blas clang clang-cuda cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 KEYWORDS=~amd64 -arm ~arm64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) <sci-chemistry/dssp-4 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
-REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) clang-cuda? ( clang cuda ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
+RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) <sci-chemistry/dssp-4
+REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) clang-cuda? ( clang cuda ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2022.3
 SRC_URI=http://ftp.gromacs.org/gromacs/gromacs-2022.3.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2022.3.pdf ) test? ( http://ftp.gromacs.org/regressiontests/regressiontests-2022.3.tar.gz )
 _eclasses_=toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	multilib	5ca4e49abed8e3a2f7b56920eadee157	bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	flag-o-matic	69394e25812406faa1f90edaf4969395	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	xdg-utils	ac0e315a3688929e34ac75b139e7349a	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	multibuild	d26d81f242cb193d899a72bca423d0bd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55
-_md5_=6017ac56695990e60fa079e1286c7ba4
+_md5_=c4f0a589fbf52e2f0caa0897259a83f9
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2022.2 b/metadata/md5-cache/sci-chemistry/gromacs-2022.4
index 037577856017..e96efe4718ec 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2022.2
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2022.4
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig clang? ( >=sys-devel/clang-6:* ) build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,10 +7,10 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=blas clang clang-cuda cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 KEYWORDS=~amd64 -arm ~arm64 ~x86 ~amd64-linux ~x86-linux ~x64-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) <sci-chemistry/dssp-4 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
-REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) clang-cuda? ( clang cuda ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
+RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) <sci-chemistry/dssp-4
+REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) clang-cuda? ( clang cuda ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
-SLOT=0/2022.2
-SRC_URI=http://ftp.gromacs.org/gromacs/gromacs-2022.2.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2022.2.pdf ) test? ( http://ftp.gromacs.org/regressiontests/regressiontests-2022.2.tar.gz )
+SLOT=0/2022.4
+SRC_URI=http://ftp.gromacs.org/gromacs/gromacs-2022.4.tar.gz doc? ( https://ftp.gromacs.org/manual/manual-2022.4.pdf ) test? ( http://ftp.gromacs.org/regressiontests/regressiontests-2022.4.tar.gz )
 _eclasses_=toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	multilib	5ca4e49abed8e3a2f7b56920eadee157	bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	flag-o-matic	69394e25812406faa1f90edaf4969395	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	xdg-utils	ac0e315a3688929e34ac75b139e7349a	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	multibuild	d26d81f242cb193d899a72bca423d0bd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55
-_md5_=6017ac56695990e60fa079e1286c7ba4
+_md5_=c4f0a589fbf52e2f0caa0897259a83f9
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2022.9999 b/metadata/md5-cache/sci-chemistry/gromacs-2022.9999
index 1ece1bea242c..032724d4a040 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2022.9999
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2022.9999
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,9 +7,9 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
 PROPERTIES=live
-RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) <sci-chemistry/dssp-4 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
-REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
+RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) <sci-chemistry/dssp-4
+REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/2022.9999
 _eclasses_=toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	multilib	5ca4e49abed8e3a2f7b56920eadee157	bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	flag-o-matic	69394e25812406faa1f90edaf4969395	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	xdg-utils	ac0e315a3688929e34ac75b139e7349a	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	multibuild	d26d81f242cb193d899a72bca423d0bd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	git-r3	2347f8fe2d392b2a091191f94be37e6f
-_md5_=763d089738fde7ef4f9fa28e4e523094
+_md5_=09de248b7cd1a170c5f0de3b80716b99
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-9999 b/metadata/md5-cache/sci-chemistry/gromacs-9999
index 7b687ce19660..f2cbd06abd9c 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-9999
+++ b/metadata/md5-cache/sci-chemistry/gromacs-9999
@@ -1,4 +1,4 @@
-BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) virtual/pkgconfig build-manual? ( app-doc/doxygen python_single_target_python3_8? ( dev-python/sphinx[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/sphinx[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/sphinx[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/sphinx[python_targets_python3_11(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) >=dev-util/ninja-1.8.2 >=dev-util/cmake-3.20.5 >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=8
@@ -7,9 +7,9 @@ INHERIT=bash-completion-r1 cmake cuda distutils-r1 flag-o-matic readme.gentoo-r1
 IUSE=blas cuda +custom-cflags +doc build-manual double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 cpu_flags_x86_avx512f cpu_flags_arm_neon python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
 PROPERTIES=live
-RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) <sci-chemistry/dssp-4 python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
-REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
+RDEPEND=blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-11[profiler] ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0= ) hwloc? ( sys-apps/hwloc:= ) lapack? ( virtual/lapack ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi[cxx] ) sci-libs/lmfit:= >=dev-cpp/muParser-2.3:= python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) <sci-chemistry/dssp-4
+REQUIRED_USE=|| ( single-precision double-precision ) doc? ( !build-manual ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0/9999
 _eclasses_=toolchain-funcs	37a4612ce5522df5a100359a8dbc8491	multilib	5ca4e49abed8e3a2f7b56920eadee157	bash-completion-r1	f5e7a020fd9c741740756aac61bf75ff	flag-o-matic	69394e25812406faa1f90edaf4969395	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	8ed38f92fe095be374d6c4c8d4c0dda7	xdg-utils	ac0e315a3688929e34ac75b139e7349a	cmake	646b7a2a63596361551a6c1fabf28057	cuda	bbef1902e3953ff9f3a9947ebf4e56f9	multibuild	d26d81f242cb193d899a72bca423d0bd	python-utils-r1	6a75203e8a499f0fb42971452ce15388	python-single-r1	a5747fe6dc0651d95cb78eddd5e160a8	distutils-r1	9c5f8e35fdc556c29573796aca3e87ea	readme.gentoo-r1	b776ad4b42f564c406a95c41ccb42c55	git-r3	2347f8fe2d392b2a091191f94be37e6f
-_md5_=763d089738fde7ef4f9fa28e4e523094
+_md5_=09de248b7cd1a170c5f0de3b80716b99
diff --git a/metadata/pkg_desc_index b/metadata/pkg_desc_index
index 5ea302f7d8d0..6431c9713ddc 100644
--- a/metadata/pkg_desc_index
+++ b/metadata/pkg_desc_index
@@ -15039,7 +15039,7 @@ net-ftp/ftpbase 0.01-r6: File Transfer Protocol (FTP) base layout
 net-ftp/gftp 2.9.1b: a free multithreaded file transfer client
 net-ftp/lftp 4.9.2 9999: A sophisticated ftp/sftp/http/https/torrent client and file transfer program
 net-ftp/linksys-tftp 1.2.1-r3: TFTP client suitable for uploading to the Linksys WRT54G Wireless Router
-net-ftp/ncftp 3.2.6-r4 3.2.6-r5: An extremely configurable ftp client
+net-ftp/ncftp 3.2.6-r5: An extremely configurable ftp client
 net-ftp/proftpd 1.3.8_rc2-r2 1.3.8: An advanced and very configurable FTP server
 net-ftp/pure-ftpd 1.0.51 9999: Fast, production-quality, standard-conformant FTP server
 net-ftp/pureadmin 0.4-r3: GUI tool used to make the management of Pure-FTPd a little easier
@@ -16305,7 +16305,7 @@ sci-chemistry/elem 1.0.3-r2: periodic table of the elements
 sci-chemistry/gelemental 2.0.0-r1 2.0.1: Periodic table viewer with detailed information on the chemical elements
 sci-chemistry/gnome-chemistry-utils 0.14.17_p6-r1: Programs and library containing GTK widgets and C++ classes related to chemistry
 sci-chemistry/gperiodic 3.0.3: Periodic table application for Linux
-sci-chemistry/gromacs 2018.8-r1 2019.6-r1 2019.6-r2 2020.4-r1 2020.7 2021.3-r1 2021.5 2021.6 2021.9999 2022.2 2022.3 2022.9999 9999: The ultimate molecular dynamics simulation package
+sci-chemistry/gromacs 2018.8-r1 2019.6-r1 2019.6-r2 2020.4-r1 2020.7 2021.3-r1 2021.5 2021.6 2021.9999 2022.3 2022.4 2022.9999 9999: The ultimate molecular dynamics simulation package
 sci-chemistry/ksdssp 040728-r1: An open source implementation of sci-chemistry/dssp
 sci-chemistry/mdtraj 1.9.4 1.9.7: Read, write and analyze MD trajectories with only a few lines of Python code
 sci-chemistry/modeller 9.25: Homology or comparative modeling of protein three-dimensional structures
diff --git a/metadata/timestamp.chk b/metadata/timestamp.chk
index 79c26e639211..6ef6890b1918 100644
--- a/metadata/timestamp.chk
+++ b/metadata/timestamp.chk
@@ -1 +1 @@
-Tue, 20 Dec 2022 18:17:10 +0000
+Tue, 20 Dec 2022 18:32:09 +0000